ABSTRACT
Cellular immunotherapy consists in using the cells of the immune system as a therapeutic weapon. In this constantly evolving field, the therapeutic strategies developed at the University Hospital of Liege are hematopoietic stem cell transplantation, mesenchymal stromal cells and targeted therapy with CAR-T cells (Chimeric Antigen Receptor T cells). The first two modalities represent a form of non-targeted cell therapy that has been developed over the past decades. While hematopoietic stem cell transplantation is established as the reference treatment for many hematological diseases, mesenchymal stromal cells are still under investigation in various pathologies (notably Crohn's disease, organ transplantation, COVID-19 and pulmonary fibrosis). By contrast, CAR-T cells represent a recently developed and extremely promising targeted immunotherapy. This therapeutic approach has already revolutionized the treatment of B-cell lymphopathies, and has the potential to do the same for many other diseases in the near future.
ABSTRACT
When faced with the news that school closures were taking place across Canada due to the Covid-19 pandemic, the small Discover the Universe team knew they wanted to support young families. Within 48 hours, Discover the Universe started an initiative to help entertain and educate youth through daily astronomy content. After 11 weeks of content, more than 50 twice-daily episodes in English and French were presented by science communicators, astronomers, physicists and an astronaut! In the first week, we saw 6,000+ live viewers. Each day, hundreds of families joined us on YouTube where all episodes are still available. The Astro at Home series is now a legacy astronomy educational resource designed for a young audience, in both offi cial languages of Canada.